document.write('<h2>Introduction</h2>')
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document.write('<u>HAT: Hypergeometric Analysis of Tiling-arrays</u><br><br>')
document.write('We have demonstrated that HAT has increased specificity for analysis of tiling-array data in comparison with alternative methods, and that it accurately detected regions-of-interest in different applications of tiling-arrays.')
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document.write('HAT has several advantages over previous methods: i) as there is no single cut-off level for probe-intensity, HAT can detect regions-of-interest at various thresholds, ii) it can detect regions-of-interest of any size, iii) it is independent of probe-resolution across the genome, and across tiling-array platforms, iv) it employs a single user defined parameter: the significance level.')
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document.write('Regions-of-interest are detected by computing the hypergeometric-probability, while controlling the Family Wise Error. Furthermore, the model does not require experimental replicates, common regions-of-interest are indicated, a sequence-of-interest can be examined for every detected region-of-interest, and flanking genes can be reported.')
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